Blood Collection Tubes

Blood collection tubes are crucial innovations employed in clinical laboratory to process, preserve and transport blood specimens for analysis. Hence these tubes are particularly made in a way that they do not affect the blood samples’ results by the laboratories. There are different kinds of blood collection tubes depending on the type of additive they contain such as anticoagulant, clot promoting solution or preservative solutions for the blood sample to be used on various tests. Each type of test, body fluid, primary reagents or other specific uses of the tubes is indicated by the colour of the tubes as follows: Glucose, Blood Chemistries, Coagulation Studies etc. They are significant for determining the precise forms of the disease and the proper treatment in medical practice.

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Nucleic Acid Test Tube

The white safety cap indicates that blood separation gel and EDTA-K2 has been added to the tube. After special treatment the DNA enzyme, RNA enzyme in the specimen can be removed by Co 60 irradiation sterilization to ensure product sterility in the test tube. Due to the addition of separation gel and the wall of the tube with good affinity, after the centrifuge, the inert separation glue can completely separate the liquid composition and the solid components in the blood and completely accumulate the barrier in the middle of the tube to maintain the stability of the specimens with heat resistance and stability.

CATEGORY: Blood Collection Tubes

Description

A Nucleic Acid Test (NAT) Tube is a specialized blood collection tube designed to preserve nucleic acids (DNA and RNA) from degradation, making it ideal for molecular diagnostic testing. The tube typically contains a stabilizing agent that prevents the degradation of nucleic acids and inhibits nuclease activity, ensuring the genetic material remains intact for accurate testing. NAT tubes are essential in detecting infectious agents, genetic mutations, and viral loads, commonly used in PCR, RT-PCR, and other molecular diagnostic techniques.

Features of Nucleic Acid Test Tube

Nucleic Acid Stabilization: Contains reagents to prevent the degradation of DNA and RNA, preserving the sample for precise testing.
Anti-Coagulant Properties: Often includes an anticoagulant to prevent clotting while ensuring the stability of nucleic acids.
Minimal Cross-Contamination: Designed to prevent contamination and maintain sample purity, which is critical in molecular diagnostics.
Extended Stability: Preserves nucleic acid integrity for longer periods, allowing for transport and delayed analysis without compromising quality.
Standardized Materials: Made from high-quality PET or glass to ensure chemical compatibility and durability during handling and storage.
Color-Coded for Molecular Use: Often features a color-coded cap (usually white or purple) for easy identification in labs focused on nucleic acid testing.

Applications of Nucleic Acid Test Tube

Infectious Disease Testing: Used to collect samples for detecting viral or bacterial nucleic acids in PCR and RT-PCR, commonly applied in testing for viruses such as HIV, Hepatitis, and COVID-19.
Genetic and Genomic Testing: Essential for collecting blood samples in genetic studies, including mutation analysis, gene expression profiling, and genomic screening.
Oncology Diagnostics: Useful in testing for circulating tumor DNA (ctDNA) and other cancer biomarkers, aiding in early cancer detection and monitoring.
Transplant Medicine: Used in molecular tests to monitor transplant patients for viral infections or rejection by measuring levels of specific nucleic acids.
Research and Development: Supports nucleic acid preservation for R&D applications, especially in pharmacogenomics, genomics research, and personalized medicine studies.